The Centcelles Villa's earliest remains date to a small rural settlement which, during the 2nd/1st century BC, harnessed the agricultural potential of the Francolí River's right flank, a natural communication route between the coast and inland planes. The first Roman villa was raised during the Imperial Era (1st/2nd century AD). Namely concerned with agricultural production, it was reformed in various stages up until the 4th century AD, when a new villa distinguished by its monumental residential quarter takes over.

Abandoned towards the end of the Late Antiquity, the structure was first transformed into the church (12th-14th century) of the town of Centcelles, then into a hermitage dedicated to Saint Bartholomew (15th-mid 19th century) and finally into a farmhouse (mid 19th-mid 20th century). It was declared World Heritage in 2000.